Reducing Operative Blood Loss in Laparoscopic Myomectomy With Umbilico-uterine Trunk Clipping

Minia University

Status: Enrolling

Conditions: Laparoscopic Myomectomy

Treatments: Procedure: umbilico-uterine trunk occlusion; Procedure: local epinephrine infiltration

Study type: Interventional

Funder types: Other

Identifiers

NCT07200778

1531-5-2025

Details and patient eligibility

About

the purpose of this study is to examine how Umbilico-uterine trunk occlusion reduces surgery-associated blood loss in Laparoscopic Myomectomy.

Enrollment: 66 estimated patients

Sex: Female

Ages: 19 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 19 and 45
• Symptoms of menorrhagia, pelvic pain, or infertility
• Plan to have a laparoscopic myomectomy
• Number of myomas ≤ 4, with the largest myoma measuring ≤ 9 cm

Exclusion criteria

• Postmenopausal status
• Dominant pedunculated subserosal FIGO classification (6-7)
• Submucosal type of myoma FIGO classification (0-2)
• Suspicion of malignant uterine or adnexal diseases
• Major medical comorbidities or psychiatric illnesses that could affect follow-up and/or compliance
• Refusal to participate or provide consent to the procedures.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

66 participants in 2 patient groups

Group A

Experimental group

Description:

participants will undergo umbilico-uterine trunk occlusion

Treatment:

Procedure: umbilico-uterine trunk occlusion

Group B

Active Comparator group

Description:

participants will undergo local injections of epinephrine into the serosal and/or myometrium, covering the myoma before the uterine incision

Treatment:

Procedure: local epinephrine infiltration