Reducing Perioperative S. Aureus Transmission Via OR PathTrac

Georgetown University

Status: Completed

Conditions: S. Aureus Transmission; Surgical Site Infection

Treatments: Other: OR PathTrac Feedback Optimization

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT04657185

00000375

Details and patient eligibility

About

Healthcare-associated infections (HAIs) occur frequently and are associated with patient harm. It is important that healthcare facilities take the necessary steps to prevent the spread of resistant bacteria. ESKAPE bacteria (Enterococcus, S. aureus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp.) are particularly pathogenic. Isolation of these pathogens from intraoperative reservoirs has been associated with postoperative infection development (i.e. surgical site infections). This project involves implementation of a software platform and bacterial collection system (OR PathTrac) that leverages the epidemiology of intraoperative bacterial transmission to guide dynamic, prospective improvements in perioperative infection control measures. The investigators will assess the effectiveness of OR PathTrac feedback in optimizing an evidence-based, multifaceted, perioperative infection control program.

Full description

Our objective was to analyze the impact of surveillance feedback optimization of a multifaceted, perioperative infection control program on S. aureus transmission and SSIs. A multifaceted infection control program was implemented over 8 months (November 2018 to June 2019). A prospective cohort impact study was then conducted over 8 months (July 2019 to March 2020) to compare the incidence of within-case S. aureus transmission (primary outcome) and surgical site infection (secondary outcome) before (4.5 months) and after (3.5 months) implementation of surveillance feedback.

Enrollment: 804 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients requiring anesthesia and intravenous catheter placement.

Exclusion criteria

• Pediatric patients, without requirement of anesthesia and/or intravenous catheter placement.

Trial design

804 participants in 2 patient groups

Before OR PathTrac Feedback

Description:

Patients undergoing surgery with an evidence-based, multifaceted, perioperative infection control program in place but without OR PathTrac feedback optimization.

After OR PathTrac Feedback

Description:

Patients undergoing surgery with an evidence-based, multifaceted, perioperative infection control program in place AND OR PathTrac feedback optimization.

Treatment:

Other: OR PathTrac Feedback Optimization