Reducing the Incidence of PostOperative Residual Curarization (PORCzero)

Oscar Diaz-Cambronero

Status: Completed

Conditions: Neuromuscular Blockade

Treatments: Behavioral: Educational program for clinicians: implementation of a package of clinical prevention measures of NMB

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03128151

CEO-SUG-2016-01

Details and patient eligibility

About

The NMB (Neuromuscular Blockade) is the most frequent complication in anesthesiology associated with an increase in adverse respiratory events in the postoperative period. Its appearance depends on multiple factors. The introduction of a comprehensive educational strategy aimed at promoting the proper management of NMB in the intraoperative period and a package of measures that must be performed (intraoperative neuromuscular monitoring and reversal of the effect of neuromuscular blockers) may contribute to a decrease in the incidence of NMB, Increase safety in the surgical patient and decrease associated costs.

Full description

Multicenter, epidemiological, prospective, randomized, sequential study. The introduction of an educational program and a package of clinical measures (specific monitoring and pharmacological reversion) in the incidence of NMB will be evaluated by evaluating variations in this incidence of NMB, the rate of compliance with the preventive measures and the perception of the Safety in the perioperative, through pre and postoperative survey.

Enrollment: 2,314 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients older than 18 years.
• Classification of the American Society of Anesthesiologists (ASA I-III).
• Patients with absence of cognitive deficit.
• Informed informed consent prior to surgery

Exclusion criteria

• Negative of the patient to participate in the study
• Patients under the age of 18 or incapable of giving their consent
• ASA IV-V
• Pregnancy or breastfeeding
• Associated neuromuscular disorders
• Diabetes mellitus with diagnosed neuropathy

Trial design

2,314 participants in 2 patient groups

Study group

Description:

Intraoperative neuromuscular monitoring and pharmacological reversion according to data sheet

Treatment:

Behavioral: Educational program for clinicians: implementation of a package of clinical prevention measures of NMB

Control group

Description:

Treated according to usual clinical practice