Reduction of Post Intravitreal Injection Bleeding and Pain by Ice

Wolfson Medical Center (WMC)

Status: Completed

Conditions: Pain

Treatments: Other: room temperature pack; Other: ice pack

Study type: Interventional

Funder types: Other

Identifiers

NCT03618875

icepreventpain

Details and patient eligibility

About

Intravitreal injections are an efficient method for delivering intraocular therapeutic agents in numerous ophthalmologic diseases. However, side effects, such as pain and subconjunctival hemorrhage remain a major concern.

Prevention or alleviation of those side effects might shorten the healing duration and improve patients' quality of life.

Full description

cooling the eye using ice patched prior to Intravitreal injections may ameliorated pain and subconjunctival hemorrhage incidences.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

patients receiving intravitreal injection

Exclusion Criteria:

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups, including a placebo group

ice

Active Comparator group

Description:

Patients were randomly assigned to receive an ice 5 minutes prior the IViT

Treatment:

Other: ice pack

placebo

Placebo Comparator group

Description:

Patients were randomly assigned to a room temperature patch (placebo) 5 minutes prior the IViT

Treatment:

Other: room temperature pack