Reference Values of Circulating Endothelial Progenitor Cells (ANOPEC2)

H

Hopital Jean Minjoz

Status

Unknown

Conditions

Aortic Aneurysm

Study type

Observational

Funder types

Other

Identifiers

NCT01918969
13/408

Details and patient eligibility

About

Circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- have been shown to be inversely correlated to aortic aneurysm size. However reference values have not yet been determined. This study is aimed to determine reference values of CD34+144+CD14- et CD34+VEGF-R2+CD14- in healthy men and women blood donors.

Full description

At the time of blood donation, 10mL of blood will be used to calculate the concentration of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- , and the ratio of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- / all circulating endothelial progenitor cells in order to determine reference values.

Enrollment

120 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Blood donors

Exclusion criteria

  • age over 65
  • Arterial hypertension (treated or not)
  • Vascular disease
  • smoker or former smoker who stopped smoking for less than a year

Trial design

120 participants in 1 patient group

Blood donors
Description:
Blood donors with no exclusion criteria i.e with a very low probability to have an aortic aneurysm

Trial contacts and locations

1

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Central trial contact

Sidney Chocron, MD, PhD; Sidney Chocron, MD,PhD

Data sourced from clinicaltrials.gov

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