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Reference Values of Circulating Endothelial Progenitor Cells (ANOPEC2)

H

Hopital Jean Minjoz

Status

Unknown

Conditions

Aortic Aneurysm

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- have been shown to be inversely correlated to aortic aneurysm size. However reference values have not yet been determined. This study is aimed to determine reference values of CD34+144+CD14- et CD34+VEGF-R2+CD14- in healthy men and women blood donors.

Full description

At the time of blood donation, 10mL of blood will be used to calculate the concentration of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- , and the ratio of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- / all circulating endothelial progenitor cells in order to determine reference values.

Enrollment

120 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Blood donors

Exclusion criteria

  • age over 65
  • Arterial hypertension (treated or not)
  • Vascular disease
  • smoker or former smoker who stopped smoking for less than a year

Trial design

120 participants in 1 patient group

Blood donors
Description:
Blood donors with no exclusion criteria i.e with a very low probability to have an aortic aneurysm

Trial contacts and locations

1

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Central trial contact

Sidney Chocron, MD,PhD; Sidney Chocron, MD, PhD

Data sourced from clinicaltrials.gov

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