Reference Values of Circulating Endothelial Progenitor Cells (ANOPEC2)

Hopital Jean Minjoz

Status: Unknown

Conditions: Aortic Aneurysm

Study type: Observational

Funder types: Other

Identifiers

NCT01918969

13/408

Details and patient eligibility

About

Circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- have been shown to be inversely correlated to aortic aneurysm size. However reference values have not yet been determined. This study is aimed to determine reference values of CD34+144+CD14- et CD34+VEGF-R2+CD14- in healthy men and women blood donors.

Full description

At the time of blood donation, 10mL of blood will be used to calculate the concentration of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- , and the ratio of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- / all circulating endothelial progenitor cells in order to determine reference values.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Blood donors

Exclusion criteria

• age over 65
• Arterial hypertension (treated or not)
• Vascular disease
• smoker or former smoker who stopped smoking for less than a year

Trial design

120 participants in 1 patient group

Blood donors

Description:

Blood donors with no exclusion criteria i.e with a very low probability to have an aortic aneurysm