Refinement and Assessment of New MRI Technologies for Thoracic/ Cardiovascular Exams

University of Michigan

Status: Completed

Conditions: Magnetic Resonance Imaging (MRI) of the Chest

Treatments: Procedure: MRI -Clinical; Procedure: MRI-Research

Study type: Interventional

Funder types: Other

Identifiers

NCT00727792

HUM00041514

Details and patient eligibility

About

The purpose of the study is to improve chest MRI exams, eventually resulting in improvements in patient care.

Full description

We will recruit patients to participate in the assessment of new MRI technologies designed to improve chest MRI exams that will result in improvements in patient care.

Several different MRI technologies will be evaluated. Specific evaluation of distinct technologies (eg. new head coil design, and new imaging sequence for the spine) may be evaluated simultaneously, or over non-overlapping periods in time.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• If you are a male or a non-pregnant female patient, age 18 years or older, of any ethnic background presenting to MRI for a clinically-ordered chest MRI exam, you are eligible to participate in this study.
• If you are a female of child bearing potential you will be questioned for the possibility of pregnancy. Pregnancy screening, if necessary, is performed routinely by ordering physicians prior to MRI scanning to confirm the patient is not pregnant.

Exclusion criteria

• Patients who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.
• Pregnant patients or patients who are nursing
• Patients who are claustrophobic.

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Group 2 - Research MRI

Experimental group

Description:

Subjects will have additional sequences and/or modification to MRI sequences.

Treatment:

Procedure: MRI-Research

Group 1 - Clinical MRI

Active Comparator group

Description:

Clinically ordered MRI scan. Subjects will not have any additional sequences or modifications to their clinically ordered MRI

Treatment:

Procedure: MRI -Clinical