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Refining the Interpretation of the Tinel's Sign for Carpal Tunnel Syndrome

A

Ahram Canadian University

Status

Enrolling

Conditions

Carpal Tunnel Syndrome

Treatments

Diagnostic Test: Tinel's Sign performed at different wrist positions

Study type

Observational

Funder types

Other

Identifiers

NCT05969093
012/TINEL2023

Details and patient eligibility

About

This is an observational study to investigate the electromyographic (EMG) activity and nerve conduction velocity (NCV) of healthy individuals during the Tinel's Sign performed at different wrist positions. The study aims to identify the wrist position that best isolates median nerve activity during the Tinel's Sign.

Full description

The study will be conducted in a controlled laboratory setting, equipped with an electromyography (EMG) machine and a nerve conduction velocity (NCV) measurement device. We will recruit 30 healthy adults, aged 18-45 years, with no history of hand or wrist pain, neurological or muscular disorders. Participants will be excluded if they have any contraindications to EMG or NCV measurement. The independent variable will be the wrist position during the Tinel's Sign, and the dependent variables will be the EMG activity of the thenar and hypothenar muscles and the NCV of the median and ulnar nerves. EMG activity will be measured using surface electrodes placed on the thenar and hypothenar muscles. NCV will be measured using a standard NCV measurement device. To minimize bias, the same trained examiner will perform all tests and measurements, and the examiner will be blinded to the EMG and NCV data during the tests. Differences in EMG activity and NCV across different wrist positions will be analyzed using repeated measures ANOVA. Post-hoc pairwise comparisons will be performed using Bonferroni correction. The study protocol will be submitted to the local ethics committee for approval, and all participants will provide informed consent.

Enrollment

30 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy individuals aged 18-45 years
  • No history of hand or wrist pain, neurological or muscular disorders

Exclusion criteria

  • Any contraindications to EMG or NCV measurement

Trial design

30 participants in 1 patient group

Healthy individuals
Description:
Participants will undergo the Tinel's Sign at different wrist positions while EMG activity and NCV are recorded.
Treatment:
Diagnostic Test: Tinel's Sign performed at different wrist positions

Trial contacts and locations

1

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Central trial contact

Mohamed M ElMeligie, Ph.d

Data sourced from clinicaltrials.gov

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