Reflective Testing for Early Diagnosis of Pituitary Dysfunction

Nova Scotia Health Authority (NSHA)

Status: Withdrawn

Conditions: Pituitary Dysfunction

Treatments: Device: Dynamic function tests and pituitary imaging; Device: Investigation for pituitary dysfunction by blood tests.

Study type: Interventional

Funder types: Other

Identifiers

NCT02406417

RTFPI2015

Details and patient eligibility

About

Early detection and management of pituitary dysfunction reduces the morbidity that ensues as a consequence of missed or delayed diagnosis of this condition, and which may result in life-threatening events and increased mortality.

The investigators study will explore the use of reflex strategies within the laboratory in capturing suspicious pituitary function test results from Primary Care patients and following these up with appropriate reflective testing. Subsequently patients identified from these results to have a possible underlying piuitary dysfunction will have an alert sent to their family physician prompting referral to the Endocrine team for further investigation and management.

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients from Primary Care found to have one or more abnormal pituitary function test picked up by the laboratory information system in the Clinical Chemistry laboratory.

Exclusion criteria

• Patients with known pituitary dysfunction or on medication that may affect pituitary function tests.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Investigation for pituitary dysfunction

Experimental group

Description:

Further investigation for pituitary dysfunction by blood tests, dynamic function tests and pituitary imaging e.g. CT Scan with contrast. Patients identified as being at high risk of having pituitary dysfunction based on preliminary blood tests will have further tests added. If these results point to a likely pituitary dysfunction, the patient will be referred to the Endocrine team for further investigations including dynamic function tests and/or imaging.

Treatment:

Device: Investigation for pituitary dysfunction by blood tests.

Device: Dynamic function tests and pituitary imaging