Reflexive Coughing Force in Severe Aspirators

The Catholic University of Korea

Status: Completed

Conditions: Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT02080988

BCMC13AH06 (Other Identifier)

HC 13OISE0066_2

Details and patient eligibility

About

To assess coughing force during reflex coughing test in those with severe dysphagia and severe aspiration and compare them to than those with stroke patients with no signs of dysphagia/aspiration.

Full description

Severe aspiration with a compromised cough function can be a risk factor of aspiration pneumonia.

Reflexive coughing can be tested by administration of citric acid via a nebulizer. The objective of this study is to measure the cough force produced via citric acid inhalation challenge, and determine if those with severe aspiration with severe dysphagia have more weak cough force during reflexive cough testing that those post-stroke patients with no signs of aspiration or dysphagia after stroke.

We also aimed to measure the strenght of the respiratory measures with the use of surface EMG.

Enrollment: 20 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Confirmed stroke lesions
• Confirmed aspiration during vfss or fees examinations

Exclusion criteria

• Episode of acute pneumonia or pulmonary embolism at time of enrollment
• Previous history of chronic respiratory disorders or other systemic disorders that may affect respiratory function ( ex, rheumatoid disease, spinal cord injury)
• Stroke patients with multiple brain lesions
• Episode of Diaphragm weakness due to peripheral polyneuropathy or unilateral phrenic nerve palsy
• Previous episode of abdominal or thoracic surgery within one year of enrollment
• Concomitant diagnosis of myopathy, muscular dystrophy or other disorders that may affect respiratory muscles.
• Episode of rib fracture within one year of enrollment
• Chronic alcoholism
• Patient with previous diagnosis of dementia or with impaired cognitive function that may limit full participation at the evaluation
• Patient with tracheostomy state

Trial design

20 participants in 2 patient groups

Silent aspirators

Description:

Stroke patients with dysphagia with severe aspiration

Non aspirating, no dysphagia group

Description:

Stroke patients with no dysphagia and no evidence of aspiration