Regenerative Endodontics for Non-vital Primary Molars

Ain Shams University

Status: Active, not recruiting

Conditions: Pulp and Periapical Tissue Disease

Treatments: Procedure: Regeneration in primary molars by using MTA; Procedure: Regeneration in primary molars by using biodentine; Procedure: Conventional Root canal treatment in primary molars

Study type: Interventional

Funder types: Other

Identifiers

NCT05098483

Ain-Shams-University

Details and patient eligibility

About

Non-vital primary molars will be treated with regenerative endodontic idea using different capping materials aiming to replace the necrotic pulp tissue with biological one and to provide perfect seal over the scaffold

Full description

Non-vital primary molars that fulfill the eligibility criteria will be randomly assigned into one of the 3 study groups:

Group 1: conventional root canal treatment Group 2: Regenerative endodontic treatment using MTA Group3: Regenerative endodontic treatment using Biodentine Each group will be followed up for 12 months

Enrollment: 39 patients

Sex: All

Ages: 4 to 7 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Non-vital mandibular primary second molar.
• Restorable tooth

Exclusion criteria

• Patients allergic to medicaments or antibiotics necessary to complete the procedure.
• Special Health Care Needs
• Excessive mobility
• Presence of internal or external root resorption.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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39 participants in 3 patient groups

Conventional root canal treatment

Active Comparator group

Description:

The caries will be removed. An excavator will be used to remove the coronal portion of the dental pulp while the radicular portion will be cleaned using k- files. 2.5% Sodium hypochlorite will be used as irrigant solution.The canals will be filled with ZOE cement and a stainless-steel crown will be inserted to restore the tooth.

Treatment:

Procedure: Conventional Root canal treatment in primary molars

Regenerative endodontic treatment using MTA

Experimental group

Description:

Access cavity will be prepared in each primary molar then each canal will be copiously irrigated by sodium hypochlorite. Triple antibiotic paste will be inserted in eash canal then sealed with temporary restoration till the second visit. In the second visit canals will be irrigated with EDTA, after that induction of bleeding will be created by overinstumentation inside each canal. Finally sealed with MTA under the GIC restoration and S.S.C

Treatment:

Procedure: Regeneration in primary molars by using MTA

Regenerative endodontic treatment using Biodentine

Experimental group

Description:

Access cavity will be prepared in each primary molar then canals will be copiously irrigated by sodium hypochlorite. Mixture of Triple antibiotic paste will be introduced in eash canal then cavity will be sealed with temporary restoration till the second visit. In the second visit canals will be irrigated with EDTA, after that bleeding will be created by overinstumentation inside each canal. Finally sealed with biodentine under the GIC restoration and S.S.C

Treatment:

Procedure: Regeneration in primary molars by using biodentine