Regenerative Endodontics in Mature Permanent Teeth

Salma fathy

Status: Completed

Conditions: Regenerative Endodontics

Treatments: Procedure: dental regenerative endodontics

Study type: Interventional

Funder types: Other

Identifiers

NCT05892536

364

Details and patient eligibility

About

this study was designed to compare the clinical and radiographic success of REPs after using blood clot scaffold in non-vital mature permanent teeth with or without photobiomodultion therapy

Enrollment: 24 patients

Sex: All

Ages: 9 to 13 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients free from any systemic diseases or genetic disorders.
• Children aged 9-13 years old of both sexes.
• Traumatically or cariously exposed single rooted mature permanent teeth which may be asymptomatic or manifested with dull ache pain, or spontaneous unprovoked toothache.
• Non-vital single rooted mature permanent teeth that indicated for endodontic treatment
• Swelling close to involved tooth accompanied with or without fistula.
• Negative response to cold & electrical pulp test.
• Informed Consent.

Exclusion criteria

• Unrestorable teeth, or that need post and core for the final restoration.
• Immature permanent teeth.
• Known allergy, sensitivity to ciprofloxacin, metronidazol.
• Uncooperativeness of child and/or parents or caregiver's behavior.
• Presence of calcific metamorphosis inside root canals.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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24 participants in 2 patient groups

blood clot regeneration

Experimental group

Description:

the regenerative procedures were performed by over-instrumentation the apices and irritating the apical tissues to induce bleeding into the root canal, then orifices plugged with MTA over blood clot and restored with GI.

Treatment:

Procedure: dental regenerative endodontics

photo-biomodulation regeneration

Active Comparator group

Description:

photobiomodulation therapy was carried out using diode laser with wavelenght 810 nm and output power 300 mW on the apical root areas of buccal and lingual surfaces at 48 hours intervals for 2 weeks after completion of the regenerative procedures which were performed by over-instrumentation the apices and irritating the apical tissues to induce bleeding into the root canal, then orifices plugged with MTA over blood clot and restored with GI.

Treatment:

Procedure: dental regenerative endodontics