Regional Anesthesia for Knee Prothesis Surgery

University of Liege

Status: Unknown

Conditions: Total Knee Replacement

Treatments: Procedure: Total knee replacement surgery.; Drug: Analgesic nerve blockade (Ropivacaine)

Study type: Interventional

Funder types: Other

Identifiers

NCT02451605

2014-000677-39

Details and patient eligibility

About

Comparison of the analgesics blocks (femoral, adductor canal and sciatic subgluteal nerve) for total replacement knee surgery.

Full description

Adductor canal block shows a beneficial effect for knee surgery. Mainly because he prevent for muscular weakness; adverse effect meet with femoral block and delaying the early active mobilization.

The investigators want to compare the efficacy and safety of this block compared to the femoral and sciatic block.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients scheduled for total knee replacement surgery.

Exclusion criteria

• refusal to study,
• coagulation disorder,
• infection at the puncture site,
• preexisting neuropathy,
• allergy to local anesthetics,
• renal or hepatocellular insufficiency,
• context of chronic pain,
• drugs abuse,
• pregnant patient.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 3 patient groups

Femoral nerve blockade

Active Comparator group

Description:

In this group, patient will benefit of an ultrasound guided femoral nerve blockade with continuous catheter infusion as (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for total knee replacement surgery.

Treatment:

Procedure: Total knee replacement surgery.

Drug: Analgesic nerve blockade (Ropivacaine)

Adductor canal blockade

Active Comparator group

Description:

In this group, patient will benefit of an ultrasound guided adductor canal blockade with continuous catheter infusion (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for for total knee replacement surgery.

Treatment:

Procedure: Total knee replacement surgery.

Drug: Analgesic nerve blockade (Ropivacaine)

Subgluteal sciatic nerve blockade

Active Comparator group

Description:

In this group, patient will benefit of an ultrasound guided subgluteal sciatic nerve blockade with continuous catheter infusion (initial bolus of 20ml of ropivacaine 0.75% follow with 7ml/hour of ropivacaine 0.2%) as analgesic nerve blockade for total knee replacement surgery.

Treatment:

Procedure: Total knee replacement surgery.

Drug: Analgesic nerve blockade (Ropivacaine)