Regional Anesthesia for Modified Radical Mastectomy With Axillary Lymph Node Dissection

Tanta University

Status and phase: Completed; Phase 3

Conditions: Breast Cancer

Treatments: Other: regional anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT04239716

mastectomy regional anesthesia

Details and patient eligibility

About

local and regional anesthesia have been introduced with the goal of reducing the side effects associated with general anesthesia and IV opioid analgesia.our hypothesis is that ultrasound-guided interscalene brachial plexus block and erector spinae plane block will provide efficient surgical anesthesia and postoperative analgesia after modified radical mastectomy.

Full description

inadequate analgesia after modified radical mastectomy with axillary lymph node dissection may occur with most of regional anesthesia. pain in the axilla and upper limb is related to ineffective block of medial and lateral pectoral nerves as long thoracic and thoracodorsal nerves, leading to inadequate analgesia.The aim of this study is to evaluate the efficacy and safety of ultrasound-guided interscalene brachial plexus block and erector spinae plane block for providing surgical anesthesia and postoperative analgesia after modified radical mastectomy.

Enrollment: 13 patients

Sex: Female

Ages: 40 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female patients aged 40-85 years old
• American Society of Anesthesiologists' physical status III and IV
• Planned for modified radical mastectomy with axillary lymph node dissection

Exclusion criteria

• Patient refusal
• Neurological or psychiatric disorders
• Local infection at injection site
• Spine or chest wall deformity
• Allergy or any contraindication to any of the study drugs
• Opioid or alcoholic addiction
• Chronic pain of any cause
• Uncooperative patients.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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13 participants in 1 patient group

regional anesthesia

Experimental group

Description:

combination of erector spinae plane block (ESPB) and interscalene block(IB).the ESPB will be performed using linear ultrasound transducer (Philips® cx 50 extreme edition, USA) and we will inject 20 ml solution(10 ml 0.5% bupivacaine, 5 ml 2% lidocaine, and 5 ml normal saline). the IB will be performed using the same ultrasound machine and injecting the same solution

Treatment:

Other: regional anesthesia