Regional Anesthesia for Thyroidectomy

Guangzhou First People's Hospital

Status: Unknown

Conditions: Chronic Pain; Acute Pain

Treatments: Procedure: placebo; Procedure: nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT02108834

GZFPH-IRB-2013-085

Details and patient eligibility

About

For more than 25 years, Regional Anesthesia has challenged anesthesiologists to determine whether it offers real benefits in terms of patient outcome from major surgery, compared with general anesthesia. Although it is clear that regional analgesia in association with general anesthesia substantially reduces postoperative pain, the benefits in terms of overall perioperative outcome are controversial. The aim of this study is to evaluate the effect on short and long-term postoperative outcomes of adding regional analgesia to general anaesthesia in thoridetomic patients.

Full description

Patients who are divided into two treatment groups: (a) a bilateral superficial cervical plexus group (group S) and a control group (group C).We performe bilateral superficial cervical plexus block (BSCPB)with 0.25-0.75% ropivacaine10 ml to group S and 10ml NaCl 0.9% to group C. All BSCPB is performed by experienced anesthesia doctor after a standardized induction of general anaesthesia.eneral anaesthesia was induced by using intravenously with midazolam,propofol, fentanyl, cisatracurium is injected IV to facilitate orotracheal intubation. After a standardized induction of general anaesthesia, patients receive Regional Anesthesia at the discretion of the experienced anesthesiologist who was blinded to treatment.

The patient is placed in a supine position with the head turned away from the side to be blocked, and then the sternocleidomastoid muscle (SCM) is identified by slight head elevation. SCPB is performed with a 26-gauge needle that is inserted at the midpoint of the posterior border of the SCM muscle and the needle is advanced just past the SCM muscle.

Enrollment: 79 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

-Eligible patients fit an ASA I or II classification adult patients who will be scheduled for elective thyroid lobectomy under general anaesthesia.

Exclusion criteria

• hypersensitivity to any study drugs
• Long-term use of anticoagulant drugs: warfarin or heparin
• the neck or systemic infection
• communication disorder
• refuse to accept this research subjects.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

79 participants in 2 patient groups, including a placebo group

nerve block

Active Comparator group

Description:

cervical plexus block with ropivacaine

Treatment:

Procedure: nerve block

Placebo

Placebo Comparator group

Description:

placebo saline

Treatment:

Procedure: placebo