Regional Distribution of Ventilation to Assess Respiratory Muscle Dysfunction (DREM)

Centre d'Investigation Clinique et Technologique 805

Status

Unknown

Conditions

Respiratory Failure

Diaphragmatic Paralysis

Neuromuscular Disorder

Study type

Observational

Funder types

Other

Identifiers

NCT01569217

11 003-CCP Ile de France XI

11.155 bis (Registry Identifier)

Details and patient eligibility

About

The aim of this study is to better discriminate respiratory muscle dysfunction by comparing the measurements of thoracoabdominal motion obtained by an optoelectronic recording and the conventional tests of respiratory muscle strength. The final objective is to better select in the future the patients who need more specific assessment of diaphragmatic function like "maximal transdiaphragmatic pressure" measurement and "phrenic nerve stimulation".

Full description

All patients which had suspected respiratory muscle dysfunction will have usual exploration of the respiratory muscles according to the clinician prescription. These explorations can include :

Lung volumes in seating and supine position
Maximal inspiratory and expiratory pressures
Maximal sniff pressures

And when diaphragmatic dysfunction is suspected :

Maximal transdiaphragmatic pressure
Phrenic nerve conduction

These patients will also beneficiate to the determination of volume variations of the upper rib cage, the lower rib cage and the abdominal compartments by using Opto-electronic plethysmography.

Enrollment

200 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria