Regional Nasal Block and Dexmedetomidine in Endoscopic Sinus Surgery

Ain Shams University

Status: Enrolling

Conditions: Drug Use

Treatments: Drug: Bupivacaine HCl 0.5% Injectable Solution; Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT05361642

FMASU MD 60/2021

Details and patient eligibility

About

The purpose is to compare the efficacy of combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery in optimizing intraoperative surgical field.

Full description

This study will be done to compare between two different techniques including regional nasal block and dexmedetomidine in optimizing intraoperative surgical field according to average category scale

Enrollment: 70 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients of ASA I or ASA II physical status.
• Patients with age 18-65 years.

Exclusion criteria

• Patients with physical status ASA III, IV.
• Known allergic reactions to local anesthetics.
• Patients with history for cerebrovascular or coronary insufficiency.
• Patients with infection at the block site.
• Patients with coagulopathy.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

regional nasal block

Active Comparator group

Description:

sphenopalatine ganglion block with general anesthesia

Treatment:

Drug: Bupivacaine HCl 0.5% Injectable Solution

dexmedetomidine

Active Comparator group

Description:

use the drug with general anesthesia

Treatment:

Drug: Dexmedetomidine