Register Study of the Neoadjuvanten Treatment by Patients With Rectumcarcinoma (HT01)

University Hospital Tuebingen

Status: Completed

Conditions: Feasibilitystudy

Study type: Observational

Funder types: Other

Identifiers

NCT03428867

UKT_RO_HT_01

Details and patient eligibility

About

goal of this study is to check the effecivity, feasibility and toxicity of the chemoradiotherapy and hyperthermia

Full description

Radiation: 5x1,8Gy until 50,4 Gy Hyperthermia: 2x/week

Chemotherapy:

neoadjuvant= day 1-5 and day 29-33 5FU 1000mg/m2 adjuvant = 4 Cycles 5FU 500mg/m2 all 4 weeks

Enrollment: 78 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

adenocarcinoma until 10 cm until ano UICC II+III 18-80 years old ECOG PS 0-2 Informed Consent

Exclusion criteria

cardiac insufficiency last 6 month heartattack nodal AV pressure III° hip prothesis cardiac pacemaker others contraindikations against the therapie radiation of pelvis chronic gestrointestinal desaese gestation or lactation previous radiotion pelvis previous Chemotherapie second carcinoma beside baslioma infiltation in analarea