Registration and Fusion of Real-Time Ultrasound With CT for Lesion Localization and Characterization

Mayo Clinic

Status: Completed

Conditions: Kidney or Liver Tumors

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00586235

06-002982

Details and patient eligibility

About

Acquire CT data and US and transducer position data (magnetic sensor system) of focal hepatic or renal lesions to serve as sample data sets for fusion algorithm development and subsequent optimization.

Full description

Acquire CT data and US and transducer position data (magnetic sensor system) of focal hepatic or renal lesions to serve as sample data sets for fusion algorithm development and subsequent optimization.

Optimize image fusion algorithms for use in goal. Develop registration algorithms that result in maximal lesional overlap with a clinically relevant difference in an epicenter location of ≤ 2 cm for lesional identification and, ultimately ≤ 0.3 cm for interventional procedures.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Focal lesion involving the liver or kidney bases on CT or MRI Imaging
• Liver lesion size >5 mm and <5 cm in diameter or renal lesion size is >5 mm and <4 cm in diameter
• Age >18 years old
• Patient has provided written informed consent

Exclusion criteria

• Patient with cardiac pacemaker or defibrillator
• Pregnant or lactating woman
• Patient with severe IV contrast allergy (previous reaction to IV contrast not mitigated by appropriate premedication)
• Patient unable to give informed consent

Trial design

80 participants in 1 patient group

1

Description:

patients with indeterminate kidney or liver lesions