Registry of Patients With Hematologic Disease and COVID-19 in Russia (CHRONOS19)

National Research Center for Hematology, Russia

Status: Completed

Conditions: Coronavirus Infection and Hematologic Diseases

Treatments: Other: Non-interventional study

Study type: Observational

Funder types: NETWORK; Other

Identifiers

NCT04422470

CHRONOS19

Details and patient eligibility

About

This is an observational prospective cohort study to evaluate the clinical course and outcomes of COVID-19 and the underlying disease in patients with hematologic disease (malignant or non-malignant).

Full description

This is a web-based registry. After registration, physicians from hematology clinical centers and hospitals in Russia will receive access to the web platform for clinical trial management to fill in the online data collection form in a de-identified manner. This form includes questions about general clinical history of hematologic disease, manifestation, treatment, and the course of COVID-19, concomitant conditions, consequences on the hematologic disease, short-term and long-term outcomes. It will take approximately 10 min to answer the questions. Patients will be followed for 30 days after COVID-19 diagnosis and up to 6 months for hematologic disease outcomes and overall survival assessment.

Enrollment: 666 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• Age 18 or older
• Any previously or currently diagnosed hematologic disease
• Laboratory confirmed or suspected (based on clinical symptoms and/or CT) COVID-19
• Known outcome of COVID-19 in case of retrospective data input (protocol allows retrospective data input for patients who were prospectively followed in local centers)

Exclusion Criteria

• Loss of follow-up within 30 days after COVID-19 diagnosis