Registry Study for Pregnant Women With Iodine Overload

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Unknown

Conditions: Iodine Overload in Pregnancy

Treatments: Other: dietary iodine restriction on subjects with iodine overload

Study type: Observational

Funder types: Other

Identifiers

NCT03470597

Liuyanping2

Details and patient eligibility

About

Pre-gestational performance of hysterosalpingography (HSG) using an oil-soluble iodinated contrast medium has been demonstrated to be the main cause of excessive iodine exposure for pregnant women. However, its long-term health effects on the mothers and offsprings have not been adequately elucidated. A case registry study is designed to follow up all the pregnant women with pre-gestational history of ethiodized-oil HSG examination and try to keep track of maternal and fetal outcomes.

Enrollment: 195 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Must be pregnant when enrolled in this study. Must have undergone examination of ethiodized-oil HSG before this pregnancy. Clinical diagnosis of iodine excess (with the mean urine iodine concentration ≥250μg/L and the serum iodine concentration >92μg/L).

Exclusion criteria

Having past history of partial or total resection of thyroid glands. Having medical history of thyroid dysfunction before ethiodized-oil HSG examination.

Trial design

195 participants in 1 patient group

Pregnant women with pre-gestational HSG history

Description:

All enrolled pregnant women with pre-gestational ethiodized-oil HSG will be followed up without grouping and be kept track for maternal and offspring's health outcomes in this case registry study.

Treatment:

Other: dietary iodine restriction on subjects with iodine overload