Rehabilitation for Improved Cognition (RECO)

Umeå University

Status: Completed

Conditions: Exhaustion; Syndrome; Burnout Syndrome

Treatments: Behavioral: Physical fitness training; Behavioral: Computer-based cognitive training

Study type: Interventional

Funder types: Other

Identifiers

NCT03073772

REHSAM 99368-2009/RS09

Details and patient eligibility

About

Many patients with exhaustion disorders continue to have significant difficulties with attention and memory function which reduce their work ability. This randomized study investigates whether the addition of a 12-week period of specific cognitive training or physical fitness training could further enhance cognitive function in patients with exhaustion disorder participating in a multimodal rehabilitation program.

Full description

This study was performed at The Stress Rehabilitation Clinic at the University hospital of Umeå. In total 161 patients with diagnosed exhaustion disorder were recruited consecutively to the study from March 2010 until June 2013. Participants were all in age span 18-60 years old, had an ongoing employment and were assessed as suitable for a 24-week multimodal rehabilitation, which consisted of cognitive behavioural therapy in group (maximum eight persons), prescription of physical activity/exercise (FaR©) and vocational measures with rehabilitation meetings. A randomization by group was performed after 12 weeks of multimodal rehabilitation to one of three conditions; A/ continued multimodal rehabilitation, B/ addition of a computer-based cognitive training, and C/ addition of physical fitness training. The added training was performed during the last 12 weeks of rehabilitation (week 12 to 24) and with three weekly training occasions. Primary endpoint was change in cognitive functioning, estimated as a global brain score. Secondary endpoints were changes in different specific neuropsychological tasks, estimated psychological wellbeing, physical capacity, work ability, health-related quality of life and cost-effectiveness. A long-term follow-up was performed one year after termination of the interventions (at week 76).

Enrollment: 161 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed exhaustion disorder according to criteria established by the Swedish National Board of Health and Welfare
• 18 - 60 years of age
• Current employment
• Considered suitable for multimodal rehabilitation in group

Exclusion criteria

• Need of other treatment or rehabilitation
• Abuse of alcohol or drugs
• Participation in another intervention study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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161 participants in 3 patient groups

Continued multimodal rehabilitation

No Intervention group

Description:

No addition of extra training in this group. Only ordinary continued multimodal rehabilitation.

Computer-based cognitive training

Active Comparator group

Description:

This arm also consisted of continued multimodal rehabilitation.

Treatment:

Behavioral: Computer-based cognitive training

Physical fitness training

Active Comparator group

Description:

This arm also consisted of continued multimodal rehabilitation.

Treatment:

Behavioral: Physical fitness training