Rehabilitation in Multiple Sclerosis: Influence of Exercise on Development of Insulin Resistance, Muscle Power and Aerobic Capacity

Hasselt University

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Behavioral: Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01718392

CME 2011/311

Details and patient eligibility

About

the purpose of this study is to investigate the development of insulin resistance in multiple sclerosis patients + explaining the effects of a combined training programme on insulin resistance, muscle power and aerobic capacity in multiple sclerosis patients

Enrollment: 45 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosed MS according to the McDonald criteria
• Expanded Disability Status Scale (EDSS) between 0.5 and 6
• Be able to train 5 times in 2 weeks at the University

Exclusion criteria

• Comorbidities like cardiovascular-, respiratory-, orthopaedic or metabolic diseases (like diabetes type 2)
• Having had an relapse in a period of 3 months prior to the start of the intervention period
• Having an relapse during the intervention period
• Pregnancy and other contra indications for physical activity
• Mental disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 2 patient groups

Training

Experimental group

Description:

24 weeks combined exercise programme (supervised)

Treatment:

Behavioral: Training

Control

No Intervention group

Description:

sedentary/habitual lifestyle