Rehabilitation of Facial Emotion Recognition in Alzheimer's Disease (EYE-TAR(MA))

Princess Grace Hospital Center (CHPG)

Status

Completed

Conditions

Alzheimer Dementia

Family Caregivers

Treatments

Other: AD-Cognitive Stimulation

Other: AD-TAR

Study type

Observational

Funder types

Other

Identifiers

NCT04730440

19-02

Details and patient eligibility

About

This study aims to evaluate impacts of an emotion recognition rehabilitation program, named Training of Affect Recognition, on social cognition abilities in Alzheimer's disease (AD). In addition, we hypothesis that the effect of this rehabilitation will also evolve gaze strategies, behavioral disorders, and the caregiver's burden.

Full description

It is commonly admitted that social cognition impairment, like deficit in facial emotion recognition or misinterpretation of others' intentions (Theory of Mind), are associated with social behavior disorders.

This kind of disorders are observed in Fronto-Temporal Dementia, Alzheimer's Dementia (AD) and Parkinson's Disease, with severe deficits in FTD and lighter deficits in AD and PD. One explanation is that patients apply inappropriate visual exploration strategies to decode emotions and intentions of others.

Our study aims to evaluate impacts of an emotion recognition rehabilitation program, named Training of Affect Recognition, on social cognition abilities (facial emotion recognition (FER) and theory of mind (ToM)) in Alzheimer's disease (AD). In addition, we hypothesis that the effect of this rehabilitation will also evolve gaze strategies, behavioral disorders, and the caregiver's burden.

Enrollment

8 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

AD diagnosed according to l'IWG-2 (Dubois & al. 2014) criteria,
Mini-Mental State (MMS-E) ≥15
Subject accompanied by a family caregiver and whose participation in a cognitive stimulation workshop was recommended in Memory Centre of the RAINIER Centre (Princesses Grace Hospital - Monaco)
Written informed consent signed by patient and family caregiver.

Exclusion criteria

General anaesthesia within 3 months.
Ophthalmological or neurological problems preventing a video-oculography examination.
Oculomotor disorders such as "fixation disorders" or "ocular tracking disorders".
Cognitive disorders of the type: visual agnosia, visuo-spatial disorder, visuo-perceptual disorder or aphasia.
History of bipolar disorder or schizophrenia
History of alcohol abuse.