Reinforcement Learned Automated Anesthesia Systems During Painless Abortion (AAS-PA)

Shenzhen United Scheme Technology

Status: Not yet enrolling

Conditions: Ciprofol; Painless Abortion; Artificial Intelligence (AI)

Treatments: Procedure: AI Controlled General Anesthesia; Procedure: General Anesthesia

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT07132151

SZUS2025002

Details and patient eligibility

About

This study compares the automated anesthesia systems for painless abortion (AAS-PA) with traditional anesthesia in painless abortions. It assesses intraoperative indicators (hypoxemia, injection pain, hypotension, hemodynamics, respiratory depression) and postoperative outcomes (nausea, dizziness, recovery time, satisfaction). The AAS-PA group uses AI-adjusted intravenous ciprofol based on real-time vital signs and sedation depth; the traditional group relies on manual anesthesia. The goal is to verify if AAS-PA safely manages sedation, meets painless standards, reduces adverse events, and improves experience, aiding optimized automated protocols.

Enrollment: 167 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between 18-45 years
• ASA status Ⅰ to Ⅱ
• Diagnosed with early intrauterine pregnancy
• Body mass index (BMI) between 18 to 28 kg/m2

Exclusion criteria

• History of cardiac, hepatic, renal, or metabolic disorders (e.g., diabetes, hypertension, sleep apnea)
• Known allergy to opioids or ciprofloxacin components
• Cachexia
• History of substance or alcohol abuse
• ASA class III or higher
• Participation in any other drug clinical trial within the past 3 months
• Long-term use of sedative or analgesic medications
• History of neurological disorders and convulsions

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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167 participants in 2 patient groups

Test group

Experimental group

Description:

In the test group, participants will receive anesthesia via an AI model.

Treatment:

Procedure: AI Controlled General Anesthesia

Control group

Experimental group

Description:

In the control group, anesthesia will be induced by experienced anesthesiologists.

Treatment:

Procedure: General Anesthesia