Reinnervation of Facial Muscles After Lengthening Temporalis Myoplasty (FacialReinn)

Caen University Hospital

Status and phase: Terminated; Phase 4

Conditions: Facial Paresis

Treatments: Drug: injection of 1% lidocaine, 2mL for facial nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT01833221

10-159

Details and patient eligibility

About

The purpose of this study is to determine the physiology of nerve healing and the neurotization of the facial muscles after lengthening temporalis myoplasty.

Full description

The investigators want to study the physiology of nerve healing after lengthening temporalis myoplasty done for facial nerve impairment. The investigators already observed few cases of spontaneous neurotization and the investigators want to check the nerve command of the facial muscles. Clinical and photographic evaluations will be performed before and after a facial nerve block using 1% lidocaine.

Enrollment: 10 patients

Sex: All

Ages: 6 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient who were operated for a facial paralysis by the lengthening temporalis myoplasty procedure in the University Hospital of Caen and who present signs of contraction of the facial muscles on the plasy side after the procedure.

Exclusion criteria

• Patient with contraindications to the injection of lidocaine
• Patient treated with beta-blocker
• Patient on anti-coagulants
• Pathology cause of facial paralysis evolving
• Pregnant or lactating
• Patient incapacitated adult
• Patient undergoing another study at the same time

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Neurotized facial muscle patients

Experimental group

Description:

injection of 1% lidocaine, 2mL for facial nerve block

Treatment:

Drug: injection of 1% lidocaine, 2mL for facial nerve block