Relationship Between Acoustic Breath Sounds and Spirometry

University Hospitals Birmingham NHS Foundation Trust (UHB)

Status: Enrolling

Conditions: Asthma COPD

Treatments: Device: Wheeze measurement

Study type: Interventional

Funder types: Other

Identifiers

NCT06039943

RKK7649

Details and patient eligibility

About

The goal of this clinical trial is to assess whether wheeze as assessed by a commercially available wheeze monitor is comparable to lung function as measured during a spirometry test. The main questions it aims to answer are whether measures of airflow obstruction (FEV1, FEV1/FVC, PEF) correlate with wheeze score (Tw/Ttot%).

Participants consenting to take part will undergo wheeze measurement prior to and during a spirometry test and will be asked to complete a series of symptom questionnaires.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consenting adult (aged 18-95) University Hospitals Birmingham patient's attending the Lung Function and Sleep Department (LF&S) routinely as part of their standard clinical management pathway for Lung Function testing that includes Spirometry assessments.
• All patients irrespective of condition will be approached to participate.

Exclusion criteria

• Subjects who are contraindicated to perform spirometry on the day of testing
• Subjects who cannot speak or read English
• Patients accessing non-adult services
• Subjects who are unable or do not wish to consent
• Patients with known or suspected restrictive lung disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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200 participants in 1 patient group

All participants

Experimental group

Description:

Participants will undergo wheeze monitoring during tidal breathing prior to spirometry and during a spirometry test.

Treatment:

Device: Wheeze measurement