Relationship Between Body Weight and Glycohemoglobin

Saitama Medical University

Status: Completed

Conditions: Type 2 Diabetes Mellitus

Study type: Observational

Funder types: Other

Identifiers

NCT00892372

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Details and patient eligibility

About

Control of body weight (BW) is important to prevent and manage type 2 diabetes. Regardless of the close association, little is understood about the precise relationship between BW and glycemic control, which might be of benefit for patients with type 2 diabetes. The researchers investigated the correlation between changes in BW and glycemic control in patients with type 2 diabetes treated with a diet therapy or pioglitazone.

Enrollment: 100 patients

Sex: All

Ages: 32 to 76 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• type 2 diabetes under reasonable glycemic control (HbA1c; less than around 7%)
• type 2 diabetic patients treated with the diet therapy

Exclusion criteria

• type 2 diabetic patients with edema, severe liver dysfunction, renal dysfunction, moderate to severe anemia or congestive heart failure
• type 2 diabetic patients treated with insulin therapy

Trial design

100 participants in 2 patient groups

1 (type 2 diabetes, body weight, HbA1c)

Description:

The investigators analyzed the recorded data (body weight and glycohemoglobin) of 70 type 2 diabetic patients treated with the diet therapy. Recorded values at 0, 2 and 4 months for body weight (BW) and glycohemoglobin (HbA1c) were used. And changes from baseline (0 month) in BW (ΔBW) were plotted against those of HbA1c (ΔHbA1c).

2 (type 2 diabetes, pioglitazone, HbA1c)

Description:

The investigators analyzed the recorded data (body weight and glycohemoglobin) of 23 type 2 diabetic patients treated with pioglitazone. Recorded values at 0, 2 and 4 months for body weight (BW)and glycohemoglobin (HbA1c) were used. And changes from baseline (0 month) in BW (ΔBW) were plotted against those of HbA1c (ΔHbA1c).