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Relationship Between Central Sensitization Levels and Treatment Outcomes in Frozen Shoulder Treatment

S

Sultan 1. Murat State Hospital

Status

Completed

Conditions

Shoulder Pain
Intra-Articular Injection
Treatment
Frozen Shoulder
Central Sensitisation

Treatments

Other: Treatment outcome

Study type

Observational

Funder types

Other

Identifiers

NCT07124689
26/06/2025-Number:37

Details and patient eligibility

About

The aim of this study was to evaluate the relationship between treatment outcomes and central sensitization levels in patients who received intra-articular injections for frozen shoulder.

Enrollment

87 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Being between 18 and 75 years of age
  • More than one-third of the active and passive movement of the painful shoulder is limited in two or more planes
  • Having pain and limited movement in the shoulder for 3-12 months

Exclusion criteria

  • Having bilateral shoulder pain
  • Patients with incomplete study data
  • Having cervical radiculopathy
  • Having a predominant central sensitization syndrome (such as fibromyalgia, chronic fatigue syndrome)
  • Patients taking antidepressants or anticonvulsants that may affect central sensitization
  • Having a history of rheumatological disease
  • Having a history of active malignancy
  • Patients receiving treatment for active psychiatric disorders
  • Having a history of trauma and/or surgery in the same shoulder region
  • Patients who received local shoulder injections and/or physical therapy within the last 3 months
  • Patients with calcific tendonitis, glenohumeral osteoarthritis, or acromioclavicular joint osteoarthritis on plain radiographs
  • Having a full-thickness rotator cuff tear on shoulder ultrasound

Trial design

87 participants in 2 patient groups

Patients with central sensitization
Description:
Patients with a score of 40 or higher on theCentral Sensitization Inventory
Treatment:
Other: Treatment outcome
Patients without central sensitization
Description:
Patients with a score below 40 on the Central Sensitization Inventory
Treatment:
Other: Treatment outcome

Trial contacts and locations

1

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Central trial contact

Alper Mengi, MD

Data sourced from clinicaltrials.gov

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