Relationship Between Circulating Tumor Stem Cells and the Clinical Pathology

Naval Military Medical University (Second Military Medical University)

Status: Completed

Conditions: Cancer Stem Cells; Postoperative Recurrence and Metastasis; Hepatocellular Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT02727673

ZD201200102-P1

Details and patient eligibility

About

The aim of this study is to establish a platform of detecting and sorting circulating tumor stem cells from peripheral blood in HCC patients; to investigate the relationship between circulating tumor stem cells and their effects on postoperative recurrence and metastasis, in order to provide a new therapeutic target for hepatocellular carcinoma treatment.

Enrollment: 1,000 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Male or female patients > 18 years and <=70 years of age;
2. No dysfunction in major organs; Blood routine, kidney function, cardiac function and lung function are basically normal.
3. Patients who can understand this trial and have signed information consent

Exclusion criteria

1. Reject to attend；
2. Impossible to come to our hospital for physical examination regularly;
3. Patients with other diseases which may affect the treatment mentioned

Trial design

1,000 participants in 3 patient groups

healthy volunteers

Description:

matched group

hepatitis cirrhosis

Description:

negative group

hepatocellular carcinoma

Description:

patients with primary HCC