Relationship Between Gestational Diabetes Mellitus and Inflammatory Adipocytokins in Obese Mothers and Their Newborn at Delivery (ADIPOGEST)

Centre Hospitalier Universitaire de la Réunion

Status: Unknown

Conditions: Diabetes, Gestational

Study type: Observational

Funder types: Other

Identifiers

NCT02905487

2012/CHU/ADIPOGEST

Details and patient eligibility

About

ADIPOGEST study aims at comparing circulating levels of inflammatory adipocytokins and C-reactive protein in obese women and their newborn at delivery whether exposed or not to Gestational Diabetes Mellitus (GDM)

Full description

ADIPOGEST is a cross sectional study in which mothers are divided into 2 groups : exposed and unexposed to GDM, matched on pregestational BMI, date of delivery and child gender.

Mothers are recruited in the maternity ward of the University Hospital in South of Reunion Island.

It is planned a conveniance sample of 20 mother-child pairs per group.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women
• Obese women (BMI : 30 kg/m² or more)
• Aged over 18 years
• With single pregnancy
• With alive newborn at 37 weeks of amenorrhea or more
• With informed consent

Exclusion criteria

• Smoker
• Treatments by corticoïds or thyroid hormons
• Overt diabetes
• Complicated pregnancy
• Premature delivery threat

Trial design

40 participants in 2 patient groups

GDM

Description:

Mother-child pairs from mothers with GDM diagnosis (ADA, 2012)

No GDM

Description:

Mother-child pairs from mothers without GDM diagnosis (ADA, 2012)