Relationship Between Mid-luteal Serum Progesterone Levels to Pregnancy Rates in Assisted Reproductive Techniques (ART)

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Infertility

Treatments: Drug: Additional vaginal progesterone

Study type: Interventional

Funder types: Other

Identifiers

NCT01356524

HYH-28-11

Details and patient eligibility

About

In Assisted Reproductive Techniques (ART) there is a need for luteal support using progesterone, estrogen and probably human chorionic gonadotropin (HCG). The optimal route of administration and dose has not yet been determined.

The aim of the study is to investigate whether high levels of mid-luteal serum progesterone are related to higher pregnancy rates in ART cycles. We also plan to investigate whether using higher doses of vaginal progesterone results in higher pregnancy rates.

Enrollment: 160 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Mid-luteal serum progesterone levels below 15 ng/dl

Exclusion criteria

• Does not sign consent form

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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160 participants in 2 patient groups

Supplementary progesterone

Active Comparator group

Description:

Women with mid-luteal progesterone levels that are less than 15 ng/dl will receive higher doses of supplementary progesterone

Treatment:

Drug: Additional vaginal progesterone

No additional progesterone

No Intervention group

Description:

No additional progesterone given to women with mid-luteal progesterone levels below 15 ng/dl