Relationship Between Muscle Mass and Muscle Relaxation Time

Go Eun Bae

Status: Completed

Conditions: Anesthesia

Treatments: Device: Inbody

Study type: Interventional

Funder types: Other

Identifiers

NCT02617433

Inbody

Details and patient eligibility

About

Rocuronium block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. There have been several studies reported positive relationship between muscle mass and amount of neuromuscular junction. The purpose of this study is to find relationship between muscle mass and muscle relaxation time.

Full description

Rocuronium block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. There have been several studies reported positive relationship between muscle mass and amount of neuromuscular junction. Until now, dose of rocuronium has been judged by patient's weight and height. However, height and weight do not represent exact muscle mass. The purpose of this study is to find relationship between muscle mass and muscle relaxation time. Measurement of muscle mass will be obtained using bioelectrical impedence analysis.

Enrollment: 42 patients

Sex: Male

Ages: 19 to 64 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All patient who undergo general anesthesia.
• Male; weight 70-75kg , height 170-175cm
• Female; weight 53-58kg , height 158-163cm

Exclusion criteria

• Liver and kidney disease
• Any types of muscle disorder.
• Metal materials or pacemaker in body

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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42 participants in 1 patient group

Inbody

Experimental group

Description:

Participant measure muscle mass by bioelectrical impedance analysis (Inbody 720, Seoul, Korea) after fast for eight hours.

Treatment:

Device: Inbody