Relationship Between NLR and Prealbumin Levels With Diaphragm Thickness

University of Indonesia (UI)

Status

Completed

Conditions

Inflammatory Response

Treatments

Diagnostic Test: Ratio of Neutrophil to Lymphocyte

Diagnostic Test: Level of Prealbumin Serum

Study type

Observational

Funder types

Other

Identifiers

NCT04014439

IndonesiaUAnes037

Details and patient eligibility

About

A study to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.

Full description

Weaning from ventilator sometimes can be failed and it happened due to several factors. One of the causes was Ventilator Induced Diaphragm Dysfunction (VIDD). This VIDD process occurred due to thinning process of the diaphragm thickness or decreased diaphragm muscle mass. The whole process happened due to inflammatory reaction that usually appeared on patients in Intensive Care Unit (ICU). Thus, this study was aimed to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.

Enrollment

30 patients

Sex

All

Ages

17 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Critical patients treated in intensive care unit using mechanical ventilation from day 0.
Patients are clinically predicted to be treated for more than 5 days (qSOFA and clinical assessment)

Exclusion criteria

History of suffering from neuromuscular disease and or diaphragmatic malformations
Used non-invasive ventilation before starting to use mechanical ventilation
History of tracheostomy
Patients admitted to ICU within 12 months before this study