Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases

The Dental Hospital of Zhejiang University School of Medicine

Status: Enrolling

Conditions: Oral Lichen Planus

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05403216

I20210609

Details and patient eligibility

About

On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.

Full description

For oral lichen planus patients, the prevalence of Hashimoto's thyroiditis will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.

Besides, for patients with Hashimoto's thyroiditis, the prevalence of oral lichen planus will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• OLP patients without systemic disease

Exclusion criteria

• OLP patients with severe periodontal disease

Trial design

60 participants in 2 patient groups

OLP(-)

Description:

Oral lichen planus (OLP) with negative thyroid antibody group

OLP(+)

Description:

OLP with positive thyroid antibody group

Treatment:

Other: no intervention