Relationship Between Pressure and Flow Velocity on Coronary Physiology

Hyogo Medical University

Status: Withdrawn

Conditions: Coronary Stenosis

Treatments: Device: combowire and IVUS

Study type: Interventional

Funder types: Other

Identifiers

NCT02330861

KFujii-000000

Details and patient eligibility

About

Subjects are patients who are planned to do percutaneous coronary intervention for coronary stenosis in the left circumflex artery without other stenosis in the left ascending artery and the right coronary artery, or a patient with normal coronary artery. Immediately after coronary angiography or percutaneous coronary intervention, the investigators will evaluate for coronary hemodynamics by distribution of wave intensity which is calcurated by coronary pressure and flow velocity with Combowire in each coronary segment. Also, they will assess coronary morphology by View It in each coronary segment.

Full description

Combowire (Volcano Therapeutics Inc., CA, USA) is a 0.014 inch pressure/Doppler sensor-tipped-guidewire which can measure coronary pressure and flow velocity.

View It (Terumo Co., Japan) is a guide catheter with intravascular ultrasound which can measure coronary morphology such as vessel diamter.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A patient who are planned to do percutaneous coronary intervention for stenosis in the left circumflex artery without any lesions in other coronary arteries
• Or a patient who is performed coronary angiography without significant stenosis lesion in 3-coronary vessel

Exclusion criteria

• A patient with coronary stenosis with LAD
• Hemodialysis
• Acute coronary syndrome
• Congestive heart failure
• A patient with shock vitals

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Normal coronary artery

Other group

Treatment:

Device: combowire and IVUS