Relationship Between Serum N/OFQ and Acute Myeloid Cell Leukemia (RBSNAAMCL)

Shanxi Medical University

Status

Not yet enrolling

Conditions

AML

Treatments

Diagnostic Test: Enzyme-linked immunosorbent assay

Study type

Observational

Funder types

Other

Identifiers

NCT06469047

Hanyi20240408

Details and patient eligibility

About

Patients diagnosed with acute myeloid leukemia in the Second Hospital of Shanxi Medical University were selected and divided into the newly diagnosed group, the relapsed group, the complete remission group as the experimental group, and the healthy physical examination subjects as the control group. The relationship between IL-1β, catecholamine and norkephalin in peripheral blood of the experimental group and the control group was observed. According to the literature, the experimental group was significantly higher than the control group. In the experimental group, the newly diagnosed group was higher than the relapse group, and the relapse group was higher than the complete remission group, and the correlation was positive, and the difference was statistically significant.

Enrollment

80 estimated patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

In accordance with adult acute myeloid leukemia (non-acute promyelocytic leukemia)The diagnostic criteria for AML in the Chinese Diagnosis and Treatment Guidelines (2017 edition); ②Leukocyte count ≤ 25×109/L;
- No treatment has been received in the past 6 months.
  - None of the candidates are related and known this study, and sign the informed consent.

Exclusion criteria

Patients who are allergic to the drugs used in this study;
- People with mental illness or cognitive impairment;
  - Patients with infectious diseases; ④Patients with severe heart, liver, kidney and other organ function lesions; ⑤ Combined with other malignant swelling. The tumor.