Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures

University of Palermo

Status: Active, not recruiting

Conditions: Osteoporosis; Hyperkyphosis; Vertebral Body Fracture

Treatments: Other: None Treatment; Other: Rehabilitation Treatment

Study type: Observational

Funder types: Other

Identifiers

NCT06842758

MFR012025

Details and patient eligibility

About

Multiple vertebral fragility fractures, one of the main complications of osteoporosis, are frequently associated with thoracic hyperkyphosis, which in turn leads to significant postural alterations.

These biomechanical changes may increase fall risk, posing a critical clinical issue for elderly patients. However, the results of studies investigating the association between hyperkyphosis and fall risk are conflicting, highlighting the need for further research.

This study aims to explore the correlation between the severity of thoracic kyphotic curvature and fall risk in patients with multiple fragility fractures undergoing osteoporosis treatment.

Additionally, the study seeks to evaluate the role of physiotherapy in improving patients' functional and postural outcomes.

A retrospective observational study was conducted, supplemented by a narrative literature review to contextualize the findings. Forty patients undergoing treatment at the Functional Recovery and Rehabilitation Unit (UOC) of P. Giaccone University Hospital in Palermo were enrolled and followed up via biannual phone interviews. Data were collected between May 2023 and May 2024, with a longitudinal assessment of outcomes from T0 (baseline) to T1 (12 months).

The severity of the kyphotic curve was quantified using the Cobb method, while fall risk was assessed through the Berg Balance Scale. Participation in physiotherapy programs was analyzed to evaluate their impact on clinical and functional outcomes.

Enrollment: 40 patients

Sex: Female

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women aged ≥65 years.
• Presence of at least three documented vertebral fragility fractures.
• Diagnosis of thoracic hyperkyphosis

Exclusion criteria

• History of orthopedic surgeries involving the spine or lower limbs.
• Treatments for cerebrovascular diseases.
• Presence of balance disorders.
• Active oncological diseases.
• Use of walking aids

Trial design

40 participants in 2 patient groups

Group A

Description:

A group of 18 women aged ≥65 years with the presence of at least three documented vertebral fragility fractures and diagnosis of thoracic hyperkyphosis.

Treatment:

Other: Rehabilitation Treatment

Group B

Description:

A group of 22 women aged ≥65 years with the presence of at least three documented vertebral fragility fractures and diagnosis of thoracic hyperkyphosis.

Treatment:

Other: None Treatment