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Relationship of Endometrial Cancer and Serum Soluble L1CAM Level

K

Kocaeli University

Status

Completed

Conditions

Endometrium Cancer

Treatments

Diagnostic Test: serum soluble L1CAM (sL1CAM)

Study type

Observational

Funder types

Other

Identifiers

NCT04603599
Merve L1CAM

Details and patient eligibility

About

The aim of this study is to evaluate the effect of serum soluble L1CAM (sL1CAM) on the diagnosis and prognosis of endometrial cancer. This prospective randomized controlled trial will be conducted in patients who have undergone endometrial biopsy and whose pathology results are reported as benign endometrial changes, endometrial hyperplasia, or endometrial cancer. The sL1CAM level between groups will be compared. The relationship between prognostic factors and serum sL1CAM will be evaluated in patients with endometrial cancer.

Enrollment

146 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients who underwent endometrial biopsy due to abnormal uterine bleeding and whose pathology results were reported as benign endometrial changes, endometrial hyperplasia or endometrial cancer were included in the study. All patients participating in the study signed informed consent.

Exclusion criteria

  • Patients who did not have consent, received neoadjuvant therapy and who would not have surgery despite endometrial cancer were excluded from the study.

Trial design

146 participants in 3 patient groups

benign endometrial changes
Treatment:
Diagnostic Test: serum soluble L1CAM (sL1CAM)
endometrial hyperplasia
Treatment:
Diagnostic Test: serum soluble L1CAM (sL1CAM)
endometrial cancer
Treatment:
Diagnostic Test: serum soluble L1CAM (sL1CAM)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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