Relationship of Essential Hypertension and Its Treatments on the Postoperative Pain Management: a Prospective, Observational, Cross-sectional Study

Kaohsiung Veterans General Hospital

Status

Unknown

Conditions

Hypertension

Study type

Observational

Funder types

Other

Identifiers

NCT02244177

VGHKS-103-080

Details and patient eligibility

About

Numbers of postoperative PCA related side effects among three groups will be determined by comparing and analyzing frequency distributions. To determine whether the patients with hypertension require less post operative opiate analgesics than others, multivariate analysis with repeated measures will be performed to identify the major and the minor factors predicting the use of postoperative pain therapy. The major aim of the study is to test the hypothesis that the morphine comsumpted by the hypertension group is less than those of the normotension group. The minor aims for the study are the difference related to pain intensity, or the incidence of side effects among groups.

Enrollment

300 estimated patients

Sex

All

Ages

20 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

300 eligible subjects
No contraindication for inhalation anesthesia
Elective surgery
Age between 20-75 y/o
No contraindication for postoperative morphine pain control
Female or male
Essential hypertension stage I and II (140<=SBP<=180; 90<=DBP<=110)

Exclusion criteria

Liver disease
Renal disease
Those who is presumed to go to ICU after surgery
The patients with dementia or conscious disturbance
Pregnancy or breast feeding
Secondary hypertension
events in recent 6 months myocardial infarction cardiac bypass surgery unstable angina cerebrovascular events congestive heart failure significant arrhythmia thoracic surgery