Relationship of Point-of-care Coagulation Assays with Clinical Outcomes in Cardiac Surgery: a Retrospective Cohort Study

University Health Network, Toronto

Status: Not yet enrolling

Conditions: Cardiac Surgery Requiring Cardiopulmonary Bypass

Treatments: Other: No intervention (observational study)

Study type: Observational

Funder types: Other

Identifiers

NCT06882759

24-5983

Details and patient eligibility

About

The goal of this observational study is to determine the relationship of ROTEM point-of-care coagulation assay parameters with excessive bleeding and clinical outcomes in patients undergoing cardiac surgery at Toronto General Hospital. The main questions it aims to answer are: i) How well does viscoelastic testing (VET) predict the clinical outcome of excessive bleeding in cardiac surgery? ii) Which VET parameters have the greatest accuracy for identification of patients who will have excessive bleeding? iii) 3) What is the prognostic value of abnormal VET parameters with other clinical outcomes after cardiac surgery?

Enrollment: 15,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients ≥ 18 years old
• Underwent a cardiac surgical procedure with cardiopulmonary bypass

Exclusion criteria

• Did not undergo viscoelastic testing during surgery

Trial design

15,000 participants in 1 patient group

Cardiac surgery patients

Description:

Adult patients undergoing cardiac surgery on cardiopulmonary bypass at Toronto General Hospital

Treatment:

Other: No intervention (observational study)