Relationships and Differences Analysis in Heart Failure (REDEAL-HF)

Wuerzburg University Hospital

Status: Enrolling

Conditions: Chronic Heart Failure; Chronic Heart Disease; Heart Failure

Treatments: Other: Time (outcome)

Study type: Observational

Funder types: Other

Identifiers

NCT03966729

REDEAL-HF

Details and patient eligibility

About

This study characterizes heart failure patients who attended the University Hospital Würzburg. The primary aim is a better understanding of the relationships and differences between the subgroups HFrEF (EF < 40%), HFmrEF (EF 40-49%), and HFpEF (EF>50%), contributing to an improved diagnosis, prognosis and therapy of patients with heart failure.

Full description

The varying clinical picture of heart failure (HF) represents a major challenge for patient care in Germany. HF is one of the most common reasons for hospitalization in the Western world. In the chronic course of heart failure, affected patients are committed to morbidity, lifelong therapy and high risk of cardiac decompensation, also associated with high mortality.

Heart failure patients, who visited the Cardiology Department of the University Hospital Wuerzburg, shall be analyzed with regard to all clinical data and outcome. This retrospective work should help to better understand the three groups HFrEF (EF < 40%), HFmrEF (EF 40-49%) and HFpEF (EF>50%) and help identifying similarities and differences between the groups.

Hereby we hope for progress in diagnostic, prognostic and therapeutic aspects of heart failure.

Enrollment: 3,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Diagnosis: Heart failure
• Minimum of two echocardiographic examinations in a minimum time frame of six months
• Patients must have reached the age of 18

Trial design

3,000 participants in 3 patient groups

HFrEF

Description:

HFrEF (Heart failure with reduced ejection fraction): ESC Guideline heart failure 2016: patients with LVEF \< 40%. LVEF = Left ventricular ejection fraction

Treatment:

Other: Time (outcome)

HFmrEF

Description:

HFmrEF (Heart failure with mid-range reduced ejection fraction): ESC Guideline heart failure 2016: patients with LVEF 40-49%. LVEF = Left ventricular ejection fraction

Treatment:

Other: Time (outcome)

HFpEF

Description:

HFmrEF (Heart failure with preserved ejection fraction): ESC Guideline heart failure 2016: patients with LVEF \> 50%. LVEF = Left ventricular ejection fraction

Treatment:

Other: Time (outcome)