Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.

Poitiers University Hospital

Status: Completed

Conditions: High Myopia

Treatments: Device: MPS II

Study type: Interventional

Funder types: Other

Identifiers

NCT02205632

MPSII-RMB

Details and patient eligibility

About

Lutein ans zeaxanthin, carotenoids provided by dietary intake are mainly located in the macular area.

Its absorption peak at 460 nm may reduce photic damages. The macular pigment density can be evaluated by its optical density.

Reduced macular pigment level is a significant risk factor for age-macular degeneration. The nutritional intake can minimise the risk of age-macular degeneration.

Enrollment: 39 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >18 years-old
• High axial myopia < -6 dioptries
• Presence or not of lacquer cracks in Bruch's membrane in one or both eyes
• Patients with social security coverage

Exclusion criteria

• Age <18 years-old
• Amblyopia in the studied eye
• Prior ocular surgery
• Corneal disease or severe dry eye syndrome
• Other retinal disease: diabetic retinopathy, age-related macular degeneration, macular hole, epiretinal membrane central
• Extensive chorioretinal atrophy
• Allergy to tropicamide
• Pregnancy

Trial design

39 participants in 2 patient groups

High myopic patients with lacker craks

Other group

Treatment:

Device: MPS II

High myopic patients without lacker cracks

Other group

Treatment:

Device: MPS II