Relevance and Efficiency of SecOnd Line Workup for Uveitis (RESOLVE)

Central Hospital, Nancy, France

Status: Not yet enrolling

Conditions: Uveitis

Treatments: Other: second line investigations for uveitis etiological workup

Study type: Observational

Funder types: Other

Identifiers

NCT06102408

2023PI190

Details and patient eligibility

About

The first-line etiological workup is currently poorly codified, and some patients undergo sequential investigations. However, the reason which lead the clinician to perform subsequent exams, and the relevance of such exams, remain to be determined. The main objective of the study was to assess the relevance of a second-line workup of patients with uveitis.

Full description

The first-line etiological workup is currently poorly codified, with some patients undergoing extensive investigations, and other minimal etiological workup. In addition, some patients undergo sequential investigations. However, the reason which lead the clinician to perform subsequent exams, and the relevance of investigations performed after a first line workup remain to be determined. The main objective of the study was to assess the relevance of a second-line workup of patients with uveitis.Secondary objectives were to describe the reasons of these second-line workups, and to determine which exams were the most relevant, and the determinants of its realization.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patient
• at least one etiological workup in our center

Exclusion criteria

• only episode of acute anterior uveitis quickly responding to topical treatments
• diagnostic ophthalmologically obvious
• opposition to collection of data

Trial design

300 participants in 3 patient groups

Patients with only one etiological workup

Description:

patients who underwent only one set of exams for etiological investigations of uveitis

Treatment:

Other: second line investigations for uveitis etiological workup

Patients without diagnostic modification subsequently to the second etiological workup

Description:

Patients who underwent a second etiological workup, independently of the results of the fist line investigations, and whose diagnosis was not modified by the second line investigations.

Treatment:

Other: second line investigations for uveitis etiological workup

Patients with diagnostic modification subsequently to the second etiological workup

Description:

Patients who underwent a second etiological workup, independently of the results of the fist line investigations, and whose diagnosis was modified by the second line investigations.

Treatment:

Other: second line investigations for uveitis etiological workup