Relevance of Sensitization to Fenugreek in Children

Central Hospital, Nancy, France

Status: Unknown

Conditions: Allergy to Fenugreek

Treatments: Diagnostic Test: Oral Food Challenge

Study type: Observational

Funder types: Other

Identifiers

NCT05340920

2021PI211

Details and patient eligibility

About

The prevalence of allergy to legumes is inscreasing, especially in children and for some of these legumes, little is known and there are not included in the list of priority allergen. The overall goal of this study is to improve knowledge about fenugreek allergy. The principal aim is to evaluate the prevalence of allergy to fenugreek confirmed by a positive oral food challenge in children sensitized to fenugreek. The secondary objectives are to describe the case of allergy to fenugreek (co-allergies, severity, age..), to evaluate diagnostic values of skin prick-tests and specific IgE and to compare the molecular profile of specific IgE to peanut between sensitization to fenugreek without allergy and sensitization with a confirmed allergy

Enrollment: 50 estimated patients

Sex: All

Ages: 1 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children for whom an oral food challenge to fenugreek has been performed between the 1st January 2017 and the 15th April 2022 and for whom skin prick test and/or specific IgE to fenugreek are avalaible

Exclusion criteria

• patient over 18 years old
• undeterminate oral food challenge