Reliability of Hammersmith Examination in Prediction of Neurological Outcomes (REHAPENO)

Abha International Private Hospital

Status: Completed

Conditions: Preterm Infant; Cerebral Palsy; Child Development Disorders

Treatments: Other: Correlation analyses for the outcomes

Study type: Observational

Funder types: Other

Identifiers

NCT03580252

Fleifel001

Details and patient eligibility

About

In this study workers are trying to test the correlation between Hammersmith Infant Neurological Examination and MRI brain/cranial ultrasound with early prediction of neurological developmental outcome of preterm neonates. This study is prospective cross-sectional collecting the data of patients according to daily standard medical practice

Full description

The primary aim of this study is to evaluate the neurobehavioural performance of infants born preterm using the Hammersmith Infant Neurological Examination (HINE) in standard medical practice and compare it with the gold standard MRI and ultrasound imagings. It would be possible to check do we need to use all the 3 examinations or Hammersmith examination would be enough reliable predictor. Secondary aim is to explore the relationships between MRI brain /cranial us abnormalities and HINE at term-equivalent age in infants born preterm in prediction of neurological outcome at 1 year of chronological age.

This study will be only single arm/single group. This group would receive the regular practice of MRI, Ultrasound (US) and Hammersmith assessments. The 3 assessments would be compared in relationships with the neonatal developmental outcomes (developmental milestones).

Enrollment: 50 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Preterm infants <37 weeks' GA at birth admitted to the neonatal nurseries at the Abha Private Hospital in Kingdom of Saudi Arabia. This project aims to recruit 50 infants <37weeks at birth over a 1-year stating from march 2018

Exclusion criteria

• -infants with congenital or chromosomal abnormalities

Trial design

50 participants in 1 patient group

Preterm Infant Neurological Follow-Up

Description:

Preterm infants \<37 weeks' gestational age (GA) at birth admitted to the neonatal nurseries at the Abha Private Hospital in Kingdom of Saudi Arabia. This project aims to recruit 50 infants \<37weeks at birth over a 1-year stating from march 2018. A Correlation analyses for the outcomes with initial regular medical practice of MRI/Ultrasound and Hammersmith assessment.

Treatment:

Other: Correlation analyses for the outcomes