Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease

University of Extremadura

Status: Active, not recruiting

Conditions: Chronic Kidney Disease; Physical Fitness; Muscle Weakness; Sarcopenia; Physical Therapy Modalities; Renal Insufficiency, Chronic

Treatments: Behavioral: Online Therapeutic Exercise; Device: Reliability Assessment

Study type: Interventional

Funder types: Other

Identifiers

NCT07292311

071125

Details and patient eligibility

About

This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Additionally, the study will assess the feasibility and potential benefits of an online therapeutic exercise program supervised by physiotherapists.

Full description

Patients with chronic kidney disease experience progressive muscle weakness and reduced physical capacity due to systemic inflammation, metabolic acidosis, and inactivity.

This two-phase observational and interventional study, conducted in collaboration with the ALCER Association (Badajoz and Cáceres, Spain), will:

1. Determine the test-retest reliability of muscle assessment tools (isokinetic dynamometer, surface electromyography, and handheld dynamometry).
2. Implement and evaluate an online therapeutic exercise program supervised by physiotherapists.

The project aims to provide valid and reliable protocols for neuromuscular assessment in CKD patients and explore the feasibility of remote therapeutic exercise.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ≥18 years old.
• Diagnosis of chronic kidney disease (hemodialysis, peritoneal dialysis, or kidney transplant).
• Member of ALCER Association (Badajoz or Cáceres).
• Medical clearance for physical testing/exercise.

Exclusion criteria

• Severe cognitive or communication impairment.
• Unstable cardiovascular or musculoskeletal conditions.
• Refusal to provide informed consent.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Reliability Assessment

Active Comparator group

Description:

Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb

Treatment:

Device: Reliability Assessment

Online Therapeutic Exercise

Experimental group

Description:

8-10 week supervised online program including resistance and mobility exercises

Treatment:

Behavioral: Online Therapeutic Exercise