Relieving the Bile Ducts Prior to Pancreatoduodenectomy

Rigshospitalet

Status: Completed

Conditions: Surgery-Complications; Pancreas Cancer; Biliary Fistula

Treatments: Procedure: Preoperative biliary drainage (ERC og PTC-aided)

Study type: Observational

Funder types: Other

Identifiers

NCT05434520

PDPTC1

Details and patient eligibility

About

The aim of this study was to assess the risk and complications after preoperative drainage of biliary obstruction in patients who underwent pancreatoduodenectomy.

A retrospective cohort study of all patients who underwent pancreatoduodenectomy from January 1st, 2015 to September 30th, 2021. Patients who had preoperative bile duct drainage were compared to patients without intervention. Type of interventions, complications and outcome after surgery were compared using univariate and multivariate analysis.

Full description

Obstructive jaundice is a common problem in pancreatic and periampullary tumors, but preoperative biliary drainage in patients with hyperbilirubinemia is still controversial. The aim of this retrospective cohort study was to assess the risk and complications after preoperative drainage of biliary obstruction in patients who underwent pancreatoduodenectomy.

A retrospective cohort study of all patients who underwent pancreatoduodenectomy from January 1st, 2015 to September 30th, 2021.

Enrollment: 722 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients who had undergone pancreatoduodenectomy

Exclusion criteria

• None

Trial design

722 participants in 2 patient groups

Preoperative biliary drainage

Description:

Patients who had undergone preoperative biliary drainage (ERC og PTC) prior to pancreatoduodenectomy

Treatment:

Procedure: Preoperative biliary drainage (ERC og PTC-aided)

No preoperative biliary drainage

Description:

Patients who had not undergone preoperative biliary drainage (ERC og PTC) prior to pancreatoduodenectomy