Remifentanil And Local Anesthesia Compared With Local Anesthesia For The Insertion Of Central Venous Catheters (REMIDOLCATH)

Toulouse University Hospital

Status and phase: Completed; Phase 4

Conditions: Local Anesthesia

Treatments: Drug: Remifentanil; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02206022

13 6932 03

Details and patient eligibility

About

At present, there is no reference protocol for Central Venous Catheter (CVC) insertion assuring analgesia, anxiolysis and safety. Medical teams use various levels of analgesia and anesthesia to realize this gesture, from single local anesthesia to general anesthesia. Remifentanil has been shown to decrease pain scores for insertion and removal of long-term central venous access. Remifentanil is also often employed for pediatric or labor analgesia for short acts as procedural sedation.

Enrollment: 90 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• more than 18 years old
• eligible for CVC insertion

Exclusion criteria

• pregnancy
• patients who can't give their consent
• contra-indications to remifentanil infusion

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 2 patient groups, including a placebo group

Remifentanil

Experimental group

Description:

Patients who undergone a Central Venous Catheter (CVC) insertion under remifentanil infusion

Treatment:

Drug: Remifentanil

Placebo

Placebo Comparator group

Description:

Patients who undergone a Central Venous Catheter (CVC) insertion under placebo infusion

Treatment:

Drug: Placebo