Remifentanil and Nitroprusside for Controlled Hypotension

Jeju National University School of Medicine

Status: Completed

Conditions: Hypotension, Controlled

Treatments: Drug: remifentanil; Drug: nitroprusside

Study type: Interventional

Funder types: Other

Identifiers

NCT02001298

HJKim3

Details and patient eligibility

About

The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension

Enrollment: 30 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who underwent endoscopic sinus surgery

Exclusion criteria

• patient who took any drug to influence this study
• patient with cardiovascular disease, renal disease or liver disease

Trial design

30 participants in 2 patient groups

nitroprusside

Experimental group

Description:

After induction of anesthesia, controlled hypotension was induced with continuous infusion of nitroprusside. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK).

Treatment:

Drug: nitroprusside

remifentanil

Experimental group

Description:

After induction of anesthesia, controlled hypotension was induced with continuous infusion of remifentanil. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK).

Treatment:

Drug: remifentanil