Remifentanil in Deep vs Moderate Neuromuscular Blocks During Surgical Pleth Index-guided Anesthesia for Laparoscopic Herniorrhaphy

Ajou University School of Medicine

Status: Completed

Conditions: Hernia Abdominal Wall

Treatments: Drug: Moderate neuromuscular block; Drug: Deep neuromuscular block

Study type: Interventional

Funder types: Other

Identifiers

NCT04022733

AJIRB-MED-THE-19-056

Details and patient eligibility

About

The primary purpose of this study is to compare the remifentanil requirements in deep versus moderate neuromuscular blocks during the surgical pleth index -guided anesthesia in patients undergoing laparoscopic herniorrhaphy.

Enrollment: 134 patients

Sex: All

Ages: 19 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• laparoscopic hernia repair

Exclusion criteria

• patients refusal, hyperbilirubinemia, chronic pain, opioid abuse, infection, and peripheral disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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134 participants in 2 patient groups, including a placebo group

Moderate NMB group

Placebo Comparator group

Treatment:

Drug: Moderate neuromuscular block

Deep NMB group

Experimental group

Treatment:

Drug: Deep neuromuscular block